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th2ax  (R&D Systems)


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    R&D Systems th2ax
    Th2ax, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 14 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/anti+h2ax/pm42013846-356-52-54?v=R%26D+Systems
    Average 93 stars, based on 14 article reviews
    th2ax - by Bioz Stars, 2026-08
    93/100 stars

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    Image Search Results


    The application of GPEVs alleviate d histopathological injury in UVB- irradiated Balb/C mice. Mice were randomly divided into five groups and subjected to a graded escalation of UVB irradiation doses in the presence or absence of GPEVs (n = 6 for each group). (A) The flow chart represents the establishment of UVB irradiation-induced skin aging model and GPEVs treatment design. (B) The skin moisture levels of mice from each group were recorded throughout the duration of the experiment. (C) Representative images of the mouse dorsal skin from each group. (D) The semi-quantitative macroscopic scoring of skin aging was assessed in each group. (E) The representative H&E images of mice skin from each group. Scale bar: 200 μm. (F) The quantification of the epidermis thickness in all five groups. (G and H) Representative immunofluorescence images and quantification of γ-H2AX in skin tissue sections. The analysis of γ-H2AX fluorescence was conducted utilizing Image J software. Data are represented as means ± SEM. Statistical analysis was performed using one-way ANOVA followed by Bonferroni post hoc test. Not significant (ns), ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.

    Journal: Bioactive Materials

    Article Title: Gynostemma pentaphyllum -derived extracellular vesicles alleviate skin aging by destabilizing STING

    doi: 10.1016/j.bioactmat.2026.03.010

    Figure Lengend Snippet: The application of GPEVs alleviate d histopathological injury in UVB- irradiated Balb/C mice. Mice were randomly divided into five groups and subjected to a graded escalation of UVB irradiation doses in the presence or absence of GPEVs (n = 6 for each group). (A) The flow chart represents the establishment of UVB irradiation-induced skin aging model and GPEVs treatment design. (B) The skin moisture levels of mice from each group were recorded throughout the duration of the experiment. (C) Representative images of the mouse dorsal skin from each group. (D) The semi-quantitative macroscopic scoring of skin aging was assessed in each group. (E) The representative H&E images of mice skin from each group. Scale bar: 200 μm. (F) The quantification of the epidermis thickness in all five groups. (G and H) Representative immunofluorescence images and quantification of γ-H2AX in skin tissue sections. The analysis of γ-H2AX fluorescence was conducted utilizing Image J software. Data are represented as means ± SEM. Statistical analysis was performed using one-way ANOVA followed by Bonferroni post hoc test. Not significant (ns), ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.

    Article Snippet: The primary antibodies used included γ-H2AX and CTCF (1:1,000, Cell Signaling), p21 and STING (diluted 1:1,000, Cell Signaling).

    Techniques: Irradiation, Immunofluorescence, Fluorescence, Software